The State of Art of Regenerative Therapy in Cardiovascular Ischemic Disease: Biology, Signaling Pathways, and Epigenetics of Endothelial Progenitor Cells
Ischemic heart disease is currently a major cause of mortality and morbidity worldwide.Nevertheless, the actual therapeutic scenario does not target myocardial cell Incontinence/Single Use regeneration and consequently, the progression toward the late stage of chronic heart failure is common.Endothelial progenitor cells (EPCs) are bone marrow-deriv